Useful life. Whole blood is collected in a citrate anticoagulant-preservative solution. The original acid-citrate-dextrose (ACD) formulation was replaced by citrate-phosphate-dextrose (CPD), which has a storage limit of 21 days when refrigerated between 1°C and 6°C. Addition of adenine (CPDA-1) increased the shelf-life to 35 days. More recently, other nutrient-additive solutions (e.g., AS-1, Adsol) have extended […]