Articles on Medical Diseases and Conditions

The various techniques just mentioned are based on different properties of protein molecules (e.g., chemical, dye-binding, electrical charge, antibody binding sites). Therefore, the different techniques may not produce identical values for all protein fractions or for individual proteins. Added to this are alterations in proteins from disease or genetic abnormalities, different interfering substances or medications, […]

There are many widely used techniques for fractionating the serum proteins. “Salting out” by differential chemical solubility yields rough separation into albumin and globulin. Cohn devised a more complicated chemical fractionation method by which certain parts of the protein spectrum may be separated from one another in a large-scale industrial-type procedure. Albumin is most often […]