Articles on Medical Diseases and Conditions

Entries Tagged ‘Red blood cell indices’

Vitamin B12 Deficiency

Vitamin B12 (cyanocobalamin) is necessary for adequate DNA synthesis through its role in folic acid metabolism. Vitamin B12 transforms metabolically inactive 5-methyl-tetrahydrofolate to tetrahydrofolate, which can then be converted to an active coenzyme. Vitamin B12 also acts as a single-carbon transfer agent in certain other metabolic pathways, such as metabolism of propionic acid. Most vitamin […]

Laboratory Tests for Chronic Iron Deficiency

Several laboratory tests are commonly used to screen for or establish a diagnosis of chronic iron deficiency. The sequence in which abnormal test results appear is given in the box below. In a normal adult on a normal diet made iron deficient by repeated phlebotomy (for experimental reasons), it takes about 3 months before significant […]