Articles on Medical Diseases and Conditions

Entries Tagged ‘Leukocyte alkaline phosphatase’

Polycythemia

Polycythemia is an increase in the total blood RBCs over the upper limit of the reference range. This usually entails a concurrent increase in hemoglobin and hematocrit values. Since various studies disagree somewhat on the values that should be considered the upper limits of normal, partially arbitrary criteria are used to define polycythemia. A hemoglobin […]

Differential Diagnosis of Chronic Myelogenous Leukemia, Agnogenic Myeloid Metaplasia, and Leukemoid Reaction

When CML has the typical picture of a WBC count more than 100,000/mm3 (100 x 109/L) with myelocytic predominance, increased platelets, and basophilia, the diagnosis is reasonably safe. Otherwise, the two conditions that most frequently enter the differential diagnosis are agnogenic myeloid metaplasia and leukemoid reaction. CML tends to have a greater degree of leukocytosis […]