Wegener’s granulomatosis is characterized by granulomatous inflammation containing foci of vasculitis involving the nasopharynx plus crescentic glomerulonephritis (proliferative vascular lesions obliterating a focal area of Bowman’s capsule space). Laboratory test abnormalities include substantial hematuria and proteinuria, and reflect a culture-negative ongoing inflammatory process. The WBC count and ESR are usually elevated when the disease is […]