Tissue-Organ Immunologic Reactions
Jul.23, 2009 in
Undesirable Effects of Blood or Blood Product Transfusion
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Graft-vs.-host disease (GVHD) Graft-vs.-host disease (GVHD) results from introduction of sufficient HLA-incompatible and immunologically competent donor lymphocytes into a recipient who is sufficiently immunodeficient that the incompatible donor cells cannot be destroyed. The donor lymphocytes proliferate and attack tissues of the new but incompatible host. There are two clinical types, organ transplants (represented here by […]