Gamma globulins (called immunoglobulins, or Igs, in current immunologic terminology) are not a homogeneous group. There are three main subdivisions: IgG, which migrates in the gamma region on electrophoresis; IgA, which migrates in the pregamma region or in the area between gamma and beta; and IgM, which migrates in the prebeta or beta region (Fig. […]
Electrophoresis is still the most commonly used screening test for serum protein abnormalities except for measurement of albumin only. Before electrophoresis was readily available, the albumin/globulin ratio was widely used; this was determined with a chemical method and should no longer be ordered, since electrophoresis not only provides the same information but also pinpoints areas […]
