Folic acid (folate) is necessary for adequate synthesis of certain purines and pyrimidines, which, in turn, are precursors of cell DNA. Folate is also necessary for methionine synthesis, histadine catabolism, and metabolism of serine and glycine. Vitamin B12 converts inactive 5-methyltetrahydrofolate to tetrahydrofolate, which is able to transfer one-carbon groups. Folic acid deficiency causes a […]