Articles on Medical Diseases and Conditions

A disease that is often very difficult to separate from CML is agnogenic (idiopathic) myeloid metaplasia (AMM). It is most common in persons aged 50-60 years. The syndrome results from bone marrow failure and subsequent extramedullary hematopoiesis on a large scale in the spleen and sometimes in the liver and lymph nodes. Actually, the extramedullary […]

Acute leukemia comprises about half of all leukemias. Acute lymphocytic leukemia (ALL) and acute nonlymphocytic leukemia (ANLL) are about equal in overall occurrence, but differ considerably in age groups. About 80%-90% of acute leukemia in childhood is ALL, and about 85%-90% in adults is ANLL (most commonly acute myelogenous leukemia and myelomonocytic leukemia). Peak incidence […]

Malignancy may occur at each major stage in the development sequence of the blood cells. In general, the earlier the stage at which the cell is involved by malignancy, the worse the prognosis. Thus, a leukemia whose predominant cell is the myeloblast has a much worse prognosis (if untreated) than one whose predominant cell is […]